The house-museum sits on Zarobyan Street in Yerevan and preserves the residence of Avetik Isahakyan, one of the most significant Armenian poets of the 20th century and a founder of modern Armenian lyric poetry. The building was decided on by the Armenian government in 1945 as a gift to Isahakyan for his 70th birthday. It was designed by architect Perch Msryan according to the poet's own wishes and built of black tuff stone, with two stories shaped to resemble an Armenian chapel, including a triangular dome and a stone porch. Isahakyan and his family moved in in 1946, and he lived there for the final decade of his life until his death in 1958. Following his death the residence was converted into a museum by government decree, and it officially opened to the public on October 31, 1963.It holds a collection of more than 10,000 items connected to Isahakyan's life and work, including manuscripts, documents, photographs, his personal library, his desk, and personal belongings such as his eyeglasses. The house is organized into a memorial section, which preserves his original office, bedroom, living room, and garden furnished as they were in his lifetime, and a literary section, which documents his written output and biography.